Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > Atf4(Gene name) > Mouse
  • Add your favorite
  • Atf4 (Gene name),
  • Cyclic AMP-dependent transcription factor ATF-4 (Protein name ),  ATF4_MOUSE from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    Atf4;
    Protein name:
    Cyclic AMP-dependent transcription factor ATF-4(cAMP-dependent transcription factor ATF-4);
    Alternative:
    C/EBP-related ATF(C/ATF);Activating transcription factor 4;Tax-responsive enhancer element-binding protein 67 homolog(TaxREB67 homolog);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with the C-terminal region of GABBR1 via the leucine zipper of its C-terminal bZIP domain. Interacts with the C-terminal region of GABBR2. Interacts with the N-terminal region of CEP290 (By similarity). Binds DNA as a homo- and heterodimer. Interaction with SATB2 results in enhanced DNA binding and transactivation by these transcription factors. Forms a heterodimer with TXLNG in osteoblasts. Interacts with NEK6.
    Function:
    Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to asymmetric CRE's as a heterodimer and to palindromic CRE's as a homodimer.
    Subcellular Location:
    Cytoplasm Cell membrane Nucleus Cytoplasm cytoskeleton centrosome Colocalizes with GABBR1 in hippocampal neuron dendritic membranes. Co-localizes with NEK6 in the centrosome.
    Protein Attributes:
    Sequence length:
    349
    Sequence:
    50:
    MTEMSFLNSE | VLAGDLMSPF | DQSGLGAEES | LGLLDDYLEV | AKHLKPHGFS | 
    100:
    SDKAGSSEWP | AMDDGLASAS | DTGKEDAFSG | TDWMLEKMDL | KEFDFDALFR | 
    150:
    MDDLETMPDE | LLTTLDDTCD | LFAPLVQETN | KEPPQTVNPI | GHLPESLIKV | 
    200:
    DQVAPFTFLQ | PFPCSPGVLS | STPEHSFSLE | LGSEVDISEG | DRKPDSAAYI | 
    250:
    TLIPPCVKEE | DTPSDNDSGI | CMSPESYLGS | PQHSPSTSRA | PPDNLPSPGG | 
    300:
    SRGSPRPKPY | DPPGVSLTAK | VKTEKLDKKL | KKMEQNKTAA | TRYRQKKRAE | 
    349:
    QEALTGECKE | LEKKNEALKE | KADSLAKEIQ | YLKDLIEEVR | KARGKKRVP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    KEGG:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse cAMP-dependent transcription factor ATF-4
    Cat.:
    E9187m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse cAMP-dependent transcription factor ATF-4
    Cat.:
    E9187b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse cAMP-dependent transcription factor ATF-4
    Cat.:
    E9187h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse cAMP-dependent transcription factor ATF-4
    Cat.:
    E9187r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse cAMP-dependent transcription factor ATF-4
    Cat.:
    U9187h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse cAMP-dependent transcription factor ATF-4
    Cat.:
    U9187m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse cAMP-dependent transcription factor ATF-4
    Cat.:
    U9187b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse cAMP-dependent transcription factor ATF-4
    Cat.:
    U9187r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse cAMP-dependent transcription factor ATF-4
    Cat.:
    P9187Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse cAMP-dependent transcription factor ATF-4
    Polyclonal Antibody for Mouse cAMP-dependent transcription factor ATF-4
    Cat.:
    P9187Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse cAMP-dependent transcription factor ATF-4
    Cat.:
    P9187Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse cAMP-dependent transcription factor ATF-4
    Monoclonal Antibody for Mouse cAMP-dependent transcription factor ATF-4
    Monoclonal Antibody for Mouse cAMP-dependent transcription factor ATF-4
    Monoclonal Antibody for Mouse cAMP-dependent transcription factor ATF-4
    Protein for Mouse cAMP-dependent transcription factor ATF-4
    Protein for Mouse cAMP-dependent transcription factor ATF-4
    Protein for Mouse cAMP-dependent transcription factor ATF-4
    Protein for Mouse cAMP-dependent transcription factor ATF-4

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "C/ATF, a member of the activating transcription factor family of DNA-binding proteins, dimerizes with CAAT/enhancer-binding proteins and directs their binding to cAMP response elements."
      Vallejo M. , Ron D. , Miller C.P. , Habener J.F.
      Proc. Natl. Acad. Sci. U.S.A.90:4679-4683(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBUNIT;SUBCELLULAR LOCATION
      tissue: Adipocyte.
    2. 2.
      "Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun."
      Chevray P.M. , Nathans D.
      Proc. Natl. Acad. Sci. U.S.A.89:5789-5793(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: CD-1.
      tissue: Embryo.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: BALB/c.
      strain: C57BL/6J.
      strain: NOD.
      tissue: Lung.
      tissue: Spinal cord.
      tissue: Spleen.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Eye.
    6. 6.
      "TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death."
      Ohoka N. , Yoshii S. , Hattori T. , Onozaki K. , Hayashi H.
      EMBO J.24:1243-1255(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    7. 7.
      "FIAT represses ATF4-mediated transcription to regulate bone mass in transgenic mice."
      Yu V.W. , Ambartsoumian G. , Verlinden L. , Moir J.M. , Prud'homme J. , Gauthier C. , Roughley P.J. , St-Arnaud R.
      J. Cell Biol.169:591-601(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TXLNG
    8. 8.
      "SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation."
      Dobreva G. , Chahrour M. , Dautzenberg M. , Chirivella L. , Kanzler B. , Farinas I. , Karsenty G. , Grosschedl R.
      Cell125:971-986(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SATB2
    9. 9.
      "FIAT is co-expressed with its dimerization target ATF4 in early osteoblasts, but not in osteocytes."
      Yu V.W. , Akhouayri O. , St-Arnaud R.
      Gene Expr. Patterns9:335-340(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE;SUBCELLULAR LOCATION
    10. 10.
      "Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA."
      Galehdar Z. , Swan P. , Fuerth B. , Callaghan S.M. , Park D.S. , Cregan S.P.
      J. Neurosci.30:16938-16948(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION
    11. 11.
      "cAMP-response element (CRE)-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 gene."
      Koyanagi S. , Hamdan A.M. , Horiguchi M. , Kusunose N. , Okamoto A. , Matsunaga N. , Ohdo S.
      J. Biol. Chem.286:32416-32423(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION
    12. 12.
      "FoxO1 protein cooperates with ATF4 protein in osteoblasts to control glucose homeostasis."
      Kode A. , Mosialou I. , Silva B.C. , Joshi S. , Ferron M. , Rached M.T. , Kousteni S.
      J. Biol. Chem.287:8757-8768(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;SUBCELLULAR LOCATION;INTERACTION WITH FOXO1;FUNCTION
    13. 13.
      "Role of activating transcription factor-4 in 24-hour rhythm of serotonin transporter expression in the mouse midbrain."
      Ushijima K. , Koyanagi S. , Sato Y. , Ogata T. , Matsunaga N. , Fujimura A. , Ohdo S.
      Mol. Pharmacol.82:264-270(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION
    14. 14.
      "The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4."
      Csibi A. , Fendt S.M. , Li C. , Poulogiannis G. , Choo A.Y. , Chapski D.J. , Jeong S.M. , Dempsey J.M. , Parkhitko A. , Morrison T. , Henske E.P. , Haigis M.C. , Cantley L.C. , Stephanopoulos G. , Yu J. , Blenis J.
      Cell153:840-854(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;UBIQUITINATION;PHOSPHORYLATION AT THR-212; SER-218; SER-223; SER-230; SER-234 AND SER-247;MUTAGENESIS OF THR-212; SER-218; SER-223; SER-230; SER-234 AND SER-247
    Product Feedback Wall
    Hot Genes
    Atf2 ASPRO ACE ALCAM C19orf80 Trap1a Gdf5
    Top Searches
    Ubiquitin-protein ligase metalloproteinase Ubiquitin ELISA Alpha Tumor necrosis Asprosin TRAP1A
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.com.cn

    Copyright & copy www.eiaab.com2006-2026 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    鄂ICP备10015095号-1

    鄂公网安备 42018502005535号

    Twitter